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I'm a paragraph. I'm connected to your collection through a dataset. To update me, go to the Data Manager. The Data Manager is where you store data to use in your site pages, or collect data from site visitors when they submit a form.
This collection in the Data Manager is already set up with some fields and content. To customize it with your own content, you can import a CSV file or simply edit the placeholder text. You can also add more fields which you can connect to other page elements so the content displays on your published site. Remember to sync the collection so your content is live! You can add as many new collections as you need to store or collect data.
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I'm a paragraph. I'm connected to your collection through a dataset. To update me, go to the Data Manager. The Data Manager is where you store data to use in your site pages, or collect data from site visitors when they submit a form.
This collection in the Data Manager is already set up with some fields and content. To customize it with your own content, you can import a CSV file or simply edit the placeholder text. You can also add more fields which you can connect to other page elements so the content displays on your published site. Remember to sync the collection so your content is live! You can add as many new collections as you need to store or collect data.
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I'm a paragraph. I'm connected to your collection through a dataset. To update me, go to the Data Manager. The Data Manager is where you store data to use in your site pages, or collect data from site visitors when they submit a form.
This collection in the Data Manager is already set up with some fields and content. To customize it with your own content, you can import a CSV file or simply edit the placeholder text. You can also add more fields which you can connect to other page elements so the content displays on your published site. Remember to sync the collection so your content is live! You can add as many new collections as you need to store or collect data.
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I'm a paragraph. I'm connected to your collection through a dataset. To update me, go to the Data Manager. The Data Manager is where you store data to use in your site pages, or collect data from site visitors when they submit a form.
This collection in the Data Manager is already set up with some fields and content. To customize it with your own content, you can import a CSV file or simply edit the placeholder text. You can also add more fields which you can connect to other page elements so the content displays on your published site. Remember to sync the collection so your content is live! You can add as many new collections as you need to store or collect data.
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I'm a paragraph. I'm connected to your collection through a dataset. To update me, go to the Data Manager. The Data Manager is where you store data to use in your site pages, or collect data from site visitors when they submit a form.
This collection in the Data Manager is already set up with some fields and content. To customize it with your own content, you can import a CSV file or simply edit the placeholder text. You can also add more fields which you can connect to other page elements so the content displays on your published site. Remember to sync the collection so your content is live! You can add as many new collections as you need to store or collect data.
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I'm a paragraph. I'm connected to your collection through a dataset. To update me, go to the Data Manager. The Data Manager is where you store data to use in your site pages, or collect data from site visitors when they submit a form.
This collection in the Data Manager is already set up with some fields and content. To customize it with your own content, you can import a CSV file or simply edit the placeholder text. You can also add more fields which you can connect to other page elements so the content displays on your published site. Remember to sync the collection so your content is live! You can add as many new collections as you need to store or collect data.
The REACH team aims at deciphering the molecular bases of the interaction between pathogens and their host plants in the context of climate change. Pathogen perception mediated by intracellular immune receptor of the NLR (nucleotide-binding Leucine rich repeat receptor) family constitutes a crucial step determining the issue of the interaction. Upon pathogen effector recognition, NLRs initiate effector-triggered immunity (ETI) that involves a rebooting of PTI-associated transcriptional reprogramming and often localized host cell death at sites of attempted pathogen infection.
Despite intensive efforts in the field, a major gap remains in our understanding of (i) how NLRs are activated by specific pathogen effectors and (ii) how the active state of these receptors connect to downstream signaling events occurring during ETI. To address those fundamental questions, we use use complementary cellular biology, molecular genetic, genomic and biochemical approaches toinvestigate the molecular events involved in ETI conditioned by plant immune receptors.
In a context of global climate change, expanding our knowledge of the interplay between plant immunity and temperature elevation is critical for developing sustainable disease resistance strategies. This includes investigating the crosstalk between NLR-mediated immunity and temperature stress responses and the identification and characterization of yet uncovered genetic sources confering robust resistance
RESEARCH THEMES
Main research axes currently developed in the REACH group :
- Virulence activities of bacterial effectors (L. Deslandes, V. Pacquit)
- Nuclear activities of a plant immune receptor complex (D. Tremousaygue, L. Deslandes, P. Dabos)
- NLR-mediated immunity at the root-level (M. Marchetti)
- Sensing and signalling activities of plant NLRs under heat stress (M. Bernoux, C. Vicédo)
- Genetic bases of robust resistances and alternatives to face pathogens in fluctuating climates (R. Berthomé)
MEMBERS
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PUBLICATIONS
Main research axes currently developed in the REACH group :
- Virulence activities of bacterial effectors (L. Deslandes, V. Pacquit)
- Nuclear activities of a plant immune receptor complex (D. Tremousaygue, L. Deslandes, P. Dabos)
- NLR-mediated immunity at the root-level (M. Marchetti)
- Sensing and signalling activities of plant NLRs under heat stress (M. Bernoux, C. Vicédo)
- Genetic bases of robust resistances and alternatives to face pathogens in fluctuating climates (R. Berthomé)
Dominique Tremousaygue
CRHC CNRS
Virginie Comorge
Doctorante
Céline Vicédo
IE CNRS
Maxime Escouboué
Doctorant